Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | PDE6A | P16499 | 1/20 | 0.35 |
| ▸ | PDE6G | P18545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE6B | P35913 | 1/20 | 0.35 |
| ▸ | PDE6C | P51160 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30990399 | 0.77 | MKNK2 (0.44) | CYP19A1 | |
| SCHEMBL38659921 | 0.75 | CYP19A1 (0.40) | KDM4ECYP11B1CYP11B2CYP3A4CYP2A6 | |
| SCHEMBL4756741 | 0.75 | CYP19A1 (0.40) | KDM4ECYP11B1CYP11B2CYP3A4CYP2A6 | |
| SCHEMBL2960574 | 0.74 | NCOA3 (0.37) | KDM4ENCOA3CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL29895259 | 0.70 | CYP11B2 (0.41) | KDM4ECYP11B2CYP3A4PARP1CYP2C19 | |
| SCHEMBL9430919 | 0.70 | CYP11B2 (0.38) | KDM4ECYP11B1CYP11B2CYP2A6PARP1 | |
| SCHEMBL1370460 | 0.69 | PARP1 (0.42) | KDM4ECYP3A4PARP1PDE2APDE6D | |
| SCHEMBL30405693 | 0.67 | CDC7 (0.51) | KDM4ECYP3A4CYP2A6PARP1CYP2E1 | |
| SCHEMBL415753 | 0.67 | CDC7 (0.51) | KDM4ECYP3A4CYP2A6PARP1CYP2E1 | |
| SCHEMBL1368544 | 0.66 | PARP1 (0.42) | KDM4ECYP3A4PARP1PDE2APDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026084957-A1 | TRICYCLIC HETEROARYL COMPOUNDS USEFUL FOR ENHANCING INNATE IMMUNE RESPONSES | ASSEMBLY BIOSCIENCES, INC. (US) | 2026-04-23 | — | — | WO | disclosed |
| EP-1641796-A1 | 5HT2C RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000849-A1 | 5HT2C RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | disclosed |