Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.77 |
| ▸ | NPC1 | O15118 | 6/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28419496 | 0.86 | RAB9A (0.76) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3939400 | 0.85 | ALDH1A1 (0.77) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3939402 | 0.85 | ALDH1A1 (0.77) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28413150 | 0.83 | RAB9A (0.70) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29577697 | 0.81 | RAB9A (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL18235526 | 0.81 | RAB9A (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4037899 | 0.81 | ALDH1A1 (0.70) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11721588 | 0.80 | MAPT (0.77) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2518089 | 0.80 | MEN1 (1.00) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9817301 | 0.79 | ALDH1A1 (0.65) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022150-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2017-01-26 | — | — | US | disclosed |
| US-20160332996-A1 | Hepatitis B Antiviral Agents | ENANTA PHARMACEUTICALS, INC. | 2016-11-17 | — | — | US | disclosed |
| EP-1559715-A4 | N-¬2-CHLORO-4-(6,7-DIMETHOXY-4-QUINOLYL)OXY|PHENYL|-N'-(5-METHYL-3-ISOXAZOLYL)UREA SALT IN CRYSTALLINE FORM | KIRIN BREWERY (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022150-A1 | HEPATITIS B ANTIVIRAL AGENTS | HAVCR2, ZC3HAV1, SLC10A1 | RAB9A 1332/4885NPC1 607/4885ALDH1A1 2749/4885 |
| US-20160332996-A1 | Hepatitis B Antiviral Agents | ZC3HAV1, ZC3HAV1L, HAVCR2 | RAB9A 1062/4885NPC1 472/4885ALDH1A1 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.