Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.83 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478927 | 0.87 | CA12 (0.67) | KMT2ACA12CA1CA9MGLL | |
| SCHEMBL10261761 | 0.86 | KMT2A (0.69) | KMT2ACA12CA1CA9HSP90AA1 | |
| SCHEMBL11692973 | 0.80 | KMT2A (0.56) | KMT2ACA12CA1CA9HSP90AA1 | |
| SCHEMBL5649903 | 0.77 | POLB (0.62) | KMT2AHSP90AA1PKMMAPK1NPSR1 | |
| SCHEMBL28503117 | 0.76 | FAAH (0.58) | KMT2ACA12CA1CA9PKM | |
| SCHEMBL1949985 | 0.76 | LMNA (0.64) | KMT2ACA12CA1CA9MGLL | |
| SCHEMBL3780616 | 0.76 | LMNA (0.67) | KMT2ACA12CA1CA9MGLL | |
| SCHEMBL6140745 | 0.76 | CA12 (0.59) | KMT2ACA12CA1CA9POLB | |
| SCHEMBL13346839 | 0.76 | CA12 (0.55) | KMT2ACA12CA1CA9POLB | |
| SCHEMBL458085 | 0.76 | CA12 (1.00) | KMT2ACA12CA1CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399498-A1 | TEXTILE COAT RUBBER COMPOSITION FOR A TIRE AND A TIRE COMPRISING A TEXTILE COAT RUBBER COMPOSITION | THE GOODYEAR TIRE & RUBBER COMPANY | 2020-12-24 | — | — | US | disclosed |
| EP-3753978-A1 | A TEXTILE COAT RUBBER COMPOSITION FOR A TIRE AND A TIRE COMPRISING A TEXTILE COAT RUBBER COMPOSITION | The Goodyear Tire & Rubber Company (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3560968-A1 | COMPOSITION, CURED PRODUCT AND LAMINATE | DIC Corporation (JP) | 2019-10-30 | — | — | EP | disclosed |
| US-9550788-B2 | Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof | SANOFI (FR) | 2017-01-24 | — | — | US | disclosed |
| US-9550788-B2 | Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof | SANOFI (FR) | 2017-01-24 | — | — | US | disclosed |
| EP-2342178-B1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI SA (FR) | 2016-09-28 | — | — | EP | disclosed |
| US-9040630-B2 | Graft copolymers of polyfarnesenes with condensation polymers | Amyris, Inc. (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140349986-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI (FR) | 2014-11-27 | — | — | US | disclosed |
| US-20140349986-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI (FR) | 2014-11-27 | — | — | US | disclosed |
| US-8822449-B2 | Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof | SANOFI (FR) | 2014-09-02 | — | — | US | disclosed |
| EP-0432941-B1 | Polyolefin-substituted amines grafted with poly (aromatic-N-monomers) for oleaginous compositions | EXXON CHEMICAL PATENTS INC (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0244898-B1 | AQUEOUS SOLUTIONS OF RESINOUS COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-07-15 | — | — | EP | disclosed |
| US-5043084-A | Novel polymer substituted amino phenol mannich base amido-amine dispersant additives (PT-742) | EXXON CHEMICAL PATENTS, INC. (US) | 1991-08-27 | — | — | US | disclosed |
| EP-0432941-A2 | Polyolefin-substituted amines grafted with poly (aromatic-N-monomers) for oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4971711-A | FUEL AND OIL ADDITIVES; AUTOMOBILE CRANKCASE OILS; AUTOMATIC TRANSMISSION FLUIDS | EXXON CHEMICAL PATENTS, INC. (US) | 1990-11-20 | — | — | US | disclosed |
| US-4820432-A | FROM LACTONE, AMINE, ALDEHYDE, HYDROXYARYLAMINE, AND HYDROCARBYL SUBSTITUTED UNSATURATED DICARBOXYLIC ACID | EXXON CHEMICAL PATENTS INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0302643-A1 | Lactone-modified mannich base dispersant additives useful in oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4769402-A | Aqueous solutions of resinous compounds | SHELL OIL COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| US-4709050-A | STABILIZING PLASTICS, POLYMERS AND RESINS TO OXIDATIVE, THERMAL AND ACTINIC DEGRADATION | CIBA-GEIGY CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0244898-A2 | Aqueous solutions of resinous compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349986-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | CFTR, AADAT, FANCI | KMT2A 3591/4885CA12 3640/4885CA1 4815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.