Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574144 | 1.00 | NOTUM (0.38) | NOTUMKMT2AMAPK1MEN1ALDH1A1 | |
| SCHEMBL4596056 | 0.84 | NOTUM (0.44) | NOTUMALDH1A1MAPTS1PR4KDM4E | |
| SCHEMBL18506606 | 0.80 | SMN1; SMN2 (0.42) | KMT2AMAPK1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6653833 | 0.80 | NOS3 (0.42) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL29383530 | 0.78 | HTT (0.35) | KMT2AMAPK1MEN1ALDH1A1GAA | |
| SCHEMBL1425084 | 0.78 | HTT (0.35) | KMT2AMAPK1MEN1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9053873 | 0.78 | SMN1; SMN2 (0.41) | KMT2AMEN1SMN1; SMN2POLBMAPT | |
| SCHEMBL11703961 | 0.78 | MAPT (0.33) | KMT2AMAPK1MEN1ALDH1A1GAA | |
| SCHEMBL17506403 | 0.78 | ADORA2A (0.44) | KMT2AMAPK1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3713130 | 0.78 | NOTUM (0.38) | NOTUMKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131938-A1 | QUINAZOLINE COMPOUND AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2024-06-27 | — | — | WO | disclosed |
| US-9708297-B2 | CGRP receptor antagonists | ELI LILLY AND COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-9637495-B2 | CGRP receptor antagonists | ELI LILLY AND COMPANY (US) | 2017-05-02 | — | — | US | disclosed |
| US-20170044138-A1 | CGRP RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2017-02-16 | — | — | US | disclosed |
| US-20170044163-A1 | CGRP RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY | 2017-02-16 | — | — | US | disclosed |
| US-20160145247-A1 | Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof | NOVARTIS AG (CH) | 2016-05-26 | — | — | US | disclosed |
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| CN-1172916-C | Oxime O-ether compounds and agricultural and horticultural fungicides | �ձ�������ʽ���� | 2004-10-27 | — | — | CN | disclosed |
| CN-1511140-A | Oxime ether compound and agricultural or horticultural bactericide | �ձ�������ʽ���� | 2004-07-07 | — | — | CN | disclosed |
| US-20040116480-A1 | Oxime ether compound and agricultural or horticultural bactericide | NIPPON SODA CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1236717-B1 | OXIME O-ETHER COMPOUNDS AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | NIPPON SODA CO (JP) | 2004-02-04 | — | — | EP | disclosed |
| EP-1362850-A1 | OXIME ETHER COMPOUND AND AGRICULTURAL OR HORTICULTURAL BACTERICIDE | NIPPON SODA CO., LTD. (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-6589967-B1 | Fungicide for agricultural and horticultural use comprising the compound as the active ingredient. agricultural plant protection chemicals have been used for controlling plant diseases. | NIPPON SODA CO. LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| CN-1387515-A | Oxime O-ether compounds and fungicides for agricultural and horticultural use | NIPPON SODA CO (JP) | 2002-12-25 | — | — | CN | disclosed |
| EP-1236717-A1 | OXIME O-ETHER COMPOUNDS AND FUNGICIDES FOR AGRICULTURAL AND HORTICULTURAL USE | NIPPON SODA CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |
| WO-1996000224-A1 | 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044163-A1 | CGRP RECEPTOR ANTAGONISTS | CALCRL, CALCR, CCKBR | NOTUM 2468/4885KMT2A 3881/4885MAPK1 1956/4885 |
| US-20160145247-A1 | Aminomethyl-Biaryl Derivatives Complement Factor D inhibitors and uses thereof | CFD, CFH, CFB | NOTUM 910/4885KMT2A 1918/4885MAPK1 4095/4885 |
| US-20170044138-A1 | CGRP RECEPTOR ANTAGONISTS | CALCRL, CALCR, CCKBR | NOTUM 2468/4885KMT2A 3881/4885MAPK1 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.