SCHEMBL5728873

SCHEMBL5728873

OC1=C(O)Oc2ccc[c]c2O1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292005 0.84
SCHEMBL206929 0.77 AHR (0.37) AHR
SCHEMBL9530690 0.70 AHR (0.57) AHR
SCHEMBL17969121 0.64
SCHEMBL103722 0.64
SCHEMBL11780383 0.62
SCHEMBL1449547 0.62
SCHEMBL4894 0.62
SCHEMBL21462 0.62 ITGB2 (0.50)
SCHEMBL2749118 0.61 MAOA (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1506179-B1 BENZOXAZINE DERIVATIVES AS 5-HT6 MODULATORS AND USES THEREOF HOFFMANN LA ROCHE (CH) 2006-01-25 EP claimed