Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 6/20 | 0.42 |
| ▸ | F13A1 | P00488 | 5/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | TGM1 | P22735 | 3/20 | 0.41 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728864 | 0.88 | STS (0.47) | STSF10TGM2F13A1GPR119 | |
| SCHEMBL5729524 | 0.86 | F10 (0.43) | STSF10 | |
| SCHEMBL7053181 | 0.85 | STS (0.48) | STSF10GPR119 | |
| SCHEMBL6887446 | 0.85 | GPR119 (0.47) | STSF10TGM2F13A1GPR119 | |
| Hydrochloric Acid SCHEMBL7535015 | 0.84 | F10 (0.43) | F10 | |
| SCHEMBL6895114 | 0.84 | STS (0.46) | STSF10GPR119 | |
| SCHEMBL5729645 | 0.83 | F10 (0.44) | F10 | |
| SCHEMBL5202414 | 0.81 | STS (0.57) | STSF10TGM2F13A1TGM1 | |
| SCHEMBL7053070 | 0.81 | STS (0.43) | STSF10GPR119 | |
| SCHEMBL7049250 | 0.80 | STS (0.43) | STSF10TGM2F13A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |