Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728783 | 0.88 | APP (0.44) | F10ALDH1A1STS | |
| SCHEMBL5728996 | 0.86 | STS (0.48) | F10STS | |
| SCHEMBL7482548 | 0.84 | F10 (0.39) | F10ALDH1A1STSF2 | |
| SCHEMBL5728780 | 0.83 | F10 (0.39) | F10ALDH1A1STSF2 | |
| SCHEMBL5729645 | 0.82 | F10 (0.44) | F10F2 | |
| SCHEMBL5728864 | 0.81 | STS (0.47) | F10ALDH1A1STS | |
| SCHEMBL5729803 | 0.79 | F10 (0.37) | F10ALDH1A1 | |
| SCHEMBL7053181 | 0.78 | STS (0.48) | F10ALDH1A1STS | |
| SCHEMBL6887446 | 0.77 | GPR119 (0.47) | F10STS | |
| SCHEMBL6895114 | 0.76 | STS (0.46) | F10ALDH1A1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188755-B1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6723722-B1 | BLOOD COAGULATION FACTOR X INHIBITORS; ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-04-20 | — | — | US | disclosed |
| EP-1188755-A1 | ACYLHYDRAZINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |