Sugi Predict

Sugi Predict / Compounds / SCHEMBL572997

SCHEMBL572997

SCHEMBL572997

Nc1ccccc1C(c1ccccc1)c1ccccc1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 2/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ CASP1 P29466 1/20 0.43
▸ CASP7 P55210 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ DPP4 P27487 2/20 0.42
▸ F2 P00734 1/20 0.42
▸ SLC6A2 P23975 3/20 0.41
▸ SLC6A4 P31645 3/20 0.41
▸ SLC6A3 Q01959 3/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ CYP2C9 P11712 2/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MTOR P42345 1/20 0.39
▸ PMP22 Q01453 1/20 0.39
▸ HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30589669 0.95 CYP3A4 (0.43) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL4845351 0.95 CYP3A4 (0.43) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL6414770 0.88 ALOX15 (0.46) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL21380569 0.87 TSHR (0.40) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL29438231 0.84 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL901197 0.84 CYP3A4 (0.53) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL5512071 0.83 LMNA (0.43) CYP3A4SMN1; SMN2ALDH1A1CYP2C9CYP2C19
SCHEMBL1357301 0.82 LMNA (0.41) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL21380576 0.82 MAOA (0.41) CYP3A4CASP1ALDH1A1CYP2C9CYP2C19
SCHEMBL30602819 0.81 CYP3A4 (0.39) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116835564-A Preparation method, specific adsorption application and adsorption equipment of bone charcoal material 中国农业大学 2023-10-03 — — CN claimed
CN-115894866-A Modified aromatic amine curing agent for storage battery sealant and preparation method thereof 杭州得力科技股份有限公司 2023-04-04 — — CN claimed
CN-112341836-B Weak acid red bisazo dye and preparation method thereof 金华恒利康化工有限公司 2021-09-21 — — CN claimed
CN-112341836-A Weak acid red bisazo dye and preparation method thereof 金华恒利康化工有限公司 2021-02-09 — — CN claimed
CN-112198141-A Method for measuring trivalent arsenic by resonance scattering spectrometry 浙江科德生物科技有限公司 2021-01-08 — — CN claimed
US-7338535-B2 Process for rapid dyeing and rapid decoloration of human keratin fibres with certain direct dyes L'OREAL S.A. (FR) 2008-03-04 — — US claimed
WO-2007017601-A1 BACTERIAL CULTURE MEDIUM IN A MINIMUM INORGANIC MEDIUM, COMPRISING GENTISATE AND/OR ONE OF THE PRECURSORS THEREOF, AND USE OF 3-HYDROXYBENZOATE IN ONE SUCH MEDIUM INSTITUT PASTEUR (FR) 2007-02-15 — — WO claimed
EP-1415643-A1 Process for rapidly colouring and decouring human keratinic fibres with direct dyes L'OREAL (FR) 2004-05-06 — — EP claimed
US-20040078906-A1 Process for rapid dyeing and rapid decoloration of human keratin fibres with certain direct dyes L'OREAL S.A. (FR) 2004-04-29 — — US claimed
EP-0257523-B1 PROCESS FOR MANUFACTURING WATER SOLUBLE TRIPHENYLMETHANE DYE COMPOUNDS OF FOODSTUFF STANDARD BASF Aktiengesellschaft (DE) 1990-01-31 — — EP claimed
US-4775451-A ELECTROLYTICALLY OXIDIZING LEUCO COMPOUNDS TO THE CORRESPONDING DYES BASF AKTIENGESELLSCHAFT (DE) 1988-10-04 — — US claimed
EP-0198303-B1 ANODIC OXIDATION PROCESS OF WATER SOLUBLE LEUCOTRIPHENYL METHANE DYE COMPOUNDS BASF Aktiengesellschaft (DE) 1988-08-17 — — EP claimed
US-4036710-A FROM AN ACIDIC BATH CONTAINING A BASIC DI- OR TRI-AMINO-TRIARYLMETHANE DYE AND A SULFOALKYL SULFIDE M & T CHEMICALS INC. (US) 1977-07-19 — — US claimed
JP-1306858-A — — None — — JP disclosed
JP-59055437-A — — None — — JP disclosed
WO-2025151354-A1 PHOTO-CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2025-07-17 — — WO disclosed
EP-0055847-A1 Pressure sensitive recording unit MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-07-14 — — EP disclosed
US-4036710-A FROM AN ACIDIC BATH CONTAINING A BASIC DI- OR TRI-AMINO-TRIARYLMETHANE DYE AND A SULFOALKYL SULFIDE M & T CHEMICALS INC. (US) 1977-07-19 — — US disclosed
US-4036710-A FROM AN ACIDIC BATH CONTAINING A BASIC DI- OR TRI-AMINO-TRIARYLMETHANE DYE AND A SULFOALKYL SULFIDE M & T CHEMICALS INC. (US) 1977-07-19 — — US disclosed
US-3960887-A Continuous process for the preparation of maleimides RHONE-POULENC S.A. (FR) 1976-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040078906-A1 Process for rapid dyeing and rapid decoloration of human keratin fibres with certain direct dyes KRT18, CYBA, TYR CYP3A4 835/4885ALOX15 3500/4885CASP1 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.