Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203973 | 0.98 | LMNA (0.81) | LMNAHRH3MEN1NPC1MITF | |
| SCHEMBL22422293 | 0.91 | LMNA (0.96) | LMNAHRH3KDM4EALDH1A1GAA | |
| SCHEMBL18926546 | 0.89 | LMNA (1.00) | LMNAHRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL17676101 | 0.86 | LMNA (0.63) | LMNAHRH3KMT2ANPSR1KDM4E | |
| SCHEMBL24474658 | 0.83 | LMNA (0.58) | LMNAHRH3MEN1NPC1MITF | |
| SCHEMBL3453099 | 0.82 | LMNA (0.79) | LMNAHRH3KDM4EALDH1A1GAA | |
| SCHEMBL5730065 | 0.81 | LMNA (0.78) | LMNAHRH3MEN1HTTKMT2A | |
| SCHEMBL5894352 | 0.81 | LMNA (0.71) | LMNAHRH3KMT2APOLBKDM4E | |
| SCHEMBL5731583 | 0.80 | LMNA (0.59) | LMNAHRH3HTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5894403 | 0.80 | LMNA (0.69) | LMNAHRH3MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420644-B1 | SUBSTITUTED PROPARGYLAMINES | BAYER CROPSCIENCE SA (FR) | 2006-05-31 | — | — | EP | claimed |