Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203973 | 0.84 | LMNA (0.81) | LMNAHRH3GRIN1POLBNPC1 | |
| SCHEMBL24474667 | 0.83 | LMNA (0.58) | LMNAHRH3GRIN1MAPK14ALDH1A1 | |
| SCHEMBL28393218 | 0.83 | LMNA (0.58) | LMNAHRH3MAPK14SMN1; SMN2ALDH1A1 | |
| SCHEMBL3634873 | 0.83 | LMNA (0.56) | LMNAHRH3GRIN1POLBSMN1; SMN2 | |
| SCHEMBL5730258 | 0.83 | LMNA (0.79) | LMNAHRH3GRIN1POLBNPC1 | |
| SCHEMBL3707475 | 0.83 | LMNA (0.49) | LMNAHRH3POLBNPC1ALDH1A1 | |
| SCHEMBL25747232 | 0.81 | LMNA (0.64) | LMNAHRH3MAPK14ALDH1A1RECQL | |
| SCHEMBL996088 | 0.80 | LMNA (0.53) | LMNAHRH3MAPK14ALDH1A1RECQL | |
| SCHEMBL2955191 | 0.79 | LMNA (0.45) | LMNAHRH3MAPK14MEN1HTT | |
| SCHEMBL13778489 | 0.77 | KCNJ5 (0.47) | LMNAMAPK14ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115326-A1 | METHODS OF MAKING A PPAR-DELTA AGONIST | RENEO PHARMACEUTICALS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |