Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5894403 | 0.98 | LMNA (0.69) | LMNAHRH3KDM4EALDH1A1PKM | |
| SCHEMBL22422293 | 0.86 | LMNA (0.96) | LMNAHRH3KDM4EALDH1A1GAA | |
| SCHEMBL18926546 | 0.84 | LMNA (1.00) | LMNAHRH3ALDH1A1KMT2AGRIN1 | |
| SCHEMBL5730258 | 0.81 | LMNA (0.79) | LMNAHRH3KDM4EALDH1A1KMT2A | |
| SCHEMBL12203973 | 0.80 | LMNA (0.81) | LMNAHRH3KDM4EALDH1A1KMT2A | |
| SCHEMBL3453099 | 0.78 | LMNA (0.79) | LMNAHRH3KDM4EALDH1A1GAA | |
| SCHEMBL5730065 | 0.78 | LMNA (0.78) | LMNAHRH3ALDH1A1KMT2AGRIN1 | |
| SCHEMBL4595408 | 0.77 | HRH3 (0.76) | LMNAHRH3LTA4H | |
| SCHEMBL4089524 | 0.77 | HRH3 (1.00) | LMNAHRH3 | |
| SCHEMBL4501961 | 0.76 | LMNA (0.81) | LMNAHRH3ALDH1A1KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060173044-A1 | Substituted propargylamines | BAYER CROPSCIENCE S.A. (FR) | 2006-08-03 | — | — | US | disclosed |
| US-7084158-B2 | Substituted propargylamines | BAYER CROPSCIENCE S.A. (FR) | 2006-08-01 | — | — | US | disclosed |
| US-20040014784-A1 | Substituted propargylamines | MERIAL, INC. | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014784-A1 | Substituted propargylamines | CBR1, CBR3, NAT1 | LMNA 3591/4885HRH3 4/4885KDM4E 1660/4885 |
| US-20060173044-A1 | Substituted propargylamines | CBR3, HRH4, HRH3 | LMNA 3592/4885HRH3 3/4885KDM4E 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.