Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5730590 | 1.00 | CCR2 (0.52) | CCR2ADRA1DADRA1AADRA1B | |
| SCHEMBL5728952 | 0.84 | CCR2 (0.71) | CCR2 | |
| SCHEMBL5728959 | 0.84 | CCR2 (0.71) | CCR2 | |
| SCHEMBL5729105 | 0.80 | PLD2 (0.54) | ADRA1DADRA1AADRA1B | |
| SCHEMBL17921966 | 0.76 | NAMPT (0.63) | — | |
| SCHEMBL17921965 | 0.76 | NAMPT (0.63) | — | |
| SCHEMBL83120 | 0.74 | DRD3 (0.62) | CCR2 | |
| SCHEMBL3079779 | 0.74 | DRD3 (0.62) | CCR2 | |
| SCHEMBL31227586 | 0.70 | JAK3 (0.48) | — | |
| SCHEMBL14587471 | 0.70 | ADRA1D (0.63) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044197-B1 | PIPERIDINYL-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKYNE CARBOXAMIDES AS CYTOSTATIC AGENTS AND IMMUNOSUPPRESSANTS | ASTELLAS PHARMA GMBH (DE) | 2006-04-19 | — | — | EP | claimed |