Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.56 |
| ▸ | NQO1 | P15559 | 5/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.55 |
| ▸ | TOP1 | P11387 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842710 | 0.85 | KDM4E (0.54) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL15980779 | 0.85 | KDM4E (0.59) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL14078661 | 0.84 | NQO1 (0.73) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL32659670 | 0.77 | VKORC1 (0.82) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL310481 | 0.77 | VKORC1 (0.82) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL13328139 | 0.76 | CYP2C9 (0.41) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL10238246 | 0.76 | CA2 (0.42) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL14078663 | 0.75 | CYP2C9 (0.72) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL1255123 | 0.74 | KDM4E (0.44) | CYP2C9NQO1CRHBPCASP7CASP6 | |
| SCHEMBL4390609 | 0.73 | NQO1 (1.00) | CYP2C9NQO1CRHBPCASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648901-A1 | SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005010006-A1 | SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-02-03 | — | — | WO | disclosed |