Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506565 | 0.80 | KEAP1 (0.58) | KEAP1NFE2L2MAOB | |
| SCHEMBL7973439 | 0.73 | KEAP1 (0.67) | KEAP1NFE2L2MAOB | |
| SCHEMBL7988040 | 0.71 | KEAP1 (0.64) | KEAP1NFE2L2MAOB | |
| SCHEMBL7388158 | 0.71 | KEAP1 (0.64) | KEAP1NFE2L2MAOB | |
| SCHEMBL2911524 | 0.70 | KEAP1 (0.63) | KEAP1NFE2L2MAOB | |
| SCHEMBL1157194 | 0.70 | KEAP1 (0.63) | KEAP1NFE2L2MAOB | |
| SCHEMBL23905132 | 0.69 | LTA4H (0.64) | KEAP1NFE2L2MAOB | |
| SCHEMBL7983918 | 0.69 | KEAP1 (0.62) | KEAP1NFE2L2MAOB | |
| SCHEMBL12990053 | 0.69 | KEAP1 (0.62) | KEAP1NFE2L2MAOB | |
| SCHEMBL12408533 | 0.69 | KEAP1 (0.62) | KEAP1NFE2L2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720836-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082859-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |