Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 5/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733609 | 0.88 | ADRB2 (0.44) | ADRB2TDP1ROCK2CDK1PRKACA | |
| SCHEMBL7691311 | 0.83 | TOP2A (0.49) | ADRB2TDP1ROCK2CDK1PRKACA | |
| SCHEMBL5733369 | 0.83 | WDR5 (0.39) | ADRB2TDP1ROCK2TSHRMAPK1 | |
| SCHEMBL5734622 | 0.82 | TOP2A (0.46) | ADRB2TDP1ROCK2CDK1PRKACA | |
| SCHEMBL5732806 | 0.82 | ADRB2 (0.43) | ADRB2TDP1ROCK2CDK1PRKACA | |
| SCHEMBL5733232 | 0.81 | TOP2A (0.48) | ADRB2TDP1TOP2ATOP2BALDH1A1 | |
| SCHEMBL5732650 | 0.81 | ADRB2 (0.43) | ADRB2TDP1ROCK2CDK1PRKACA | |
| SCHEMBL5744355 | 0.80 | ADRB2 (0.42) | ADRB2TDP1ROCK2CDK1PRKACA | |
| SCHEMBL5734038 | 0.80 | TOP2A (0.47) | TOP2ATOP2BKCNH2 | |
| SCHEMBL5733582 | 0.79 | ADRB2 (0.42) | ADRB2TDP1TOP2ATOP2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070713-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-6335447-B1 | BACTERICIDES | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1070713-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |