SCHEMBL573401

SCHEMBL573401

N#CCC(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2214877 0.93 MCL1 (0.39)
Acetic Acid SCHEMBL1991353 0.91 MCL1 (0.38)
SCHEMBL1011084 0.81
SCHEMBL15156953 0.79
SCHEMBL1012319 0.79
SCHEMBL1014847 0.79 MCL1 (0.40)
SCHEMBL24410357 0.75 MCL1 (0.38)
SCHEMBL1013569 0.75 MCL1 (0.38)
SCHEMBL1583542 0.75 MCL1 (0.40)
SCHEMBL3391018 0.75 MCL1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63264448-A None JP disclosed
US-12611404-B2 Aza-aryl 1H-pyrazol-1-yl benzene sulfonamides CHEMOCENTRYX, INC. (US) 2026-04-28 US disclosed
US-20250382304-A1 HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS NUVALENT INC (US) 2025-12-18 US disclosed
US-12358906-B2 Urea compounds and compositions as SMARCA2/BRM ATPase inhibitors NOVARTIS AG (CH) 2025-07-15 US disclosed
WO-2025137516-A1 FLUORINATED MONOMERS, ANION EXCHANGE POLYMERS AND METHODS OF MAKING THE SAME THE CHEMOURS COMPANY FC, LLC (US) 2025-06-26 WO disclosed
US-12275742-B2 Heteroaromatic macrocyclic ether chemotherapeutic agents NUVALENT, INC. (US) 2025-04-15 US disclosed
WO-2025067411-A1 NEK7 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京普祺医药科技股份有限公司 2025-04-03 WO disclosed
WO-2025002289-A1 PYRAZOLOHETEROARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖南九典制药股份有限公司 2025-01-02 WO disclosed
CN-119219638-A Pyrazoloheteroaryl compound and preparation method and application thereof 湖南九典制药股份有限公司 2024-12-31 CN disclosed
EP-4244910-B1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2024-12-11 EP disclosed
EP-0375670-A2 Process for preparing 3-polyfluoroalkylisoxazolylamines SHIONOGI & CO., LTD. (JP) 1990-06-27 EP disclosed
US-4910326-A β-ketonitrils SHIONOGI & CO., LTD. (JP) 1990-03-20 US disclosed
WO-1989008664-A1 SYNTHETIC PEPTIDE ANTIGENS FOR THE DETECTION OF HTLV-1 INFECTION VIROVAHL S.A. (CH) 1989-09-21 WO disclosed
US-4829076-A CARDIOVASCULAR DISORDERS ALKALOIDA VEGYESZETI GYAR (HU) 1989-05-09 US disclosed
EP-0304966-A2 Beta-ketonitriles SHIONOGI & CO., LTD. (JP) 1989-03-01 EP disclosed
US-4797492-A INTERMEDIATES FOR BACTERICIDES; HERBICIDES OR FUNGICIDES SHIONOGI & CO., LTD. (JP) 1989-01-10 US disclosed
EP-0292454-A2 Synthetic peptide antigen for the detection of HIV-2 infection SYNTELLO AB (SE) 1988-11-23 EP disclosed
JP-S63264448-A NOVEL BETA-KETONITRILE SHIONOGI & CO LTD 1988-11-01 JP disclosed
EP-0284587-A2 Synthetic peptide antigens for the detection of HIV-1 infection SYNTELLO AB (SE) 1988-09-28 EP disclosed
EP-0220947-A2 Polyfluoroalkylisoxazolylamines, their preparation and use SHIONOGI & CO., LTD. (JP) 1987-05-06 EP disclosed