Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 6/20 | 0.34 |
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573401 | 0.93 | — | — | |
| Acetic Acid SCHEMBL1991353 | 0.88 | MCL1 (0.38) | MCL1CES1FAAHCES2CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL21226529 | 0.77 | MCL1 (0.36) | MCL1 | |
| Trifluoroacetic Acid SCHEMBL28832532 | 0.76 | ALDH1A1 (0.36) | CES1 | |
| Trifluoroacetic Acid SCHEMBL7080470 | 0.76 | MCL1 (0.44) | MCL1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL23043751 | 0.75 | ALDH1A1 (0.47) | MCL1CES1FAAHCES2CYP1A2 | |
| SCHEMBL1011084 | 0.75 | — | — | |
| Trifluoroacetic Acid SCHEMBL27350364 | 0.75 | ALDH1A1 (0.47) | MCL1CES1FAAHCES2CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL9416914 | 0.73 | CA2 (0.40) | CES1 | |
| SCHEMBL1014847 | 0.73 | MCL1 (0.40) | MCL1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219713-B1 | PROCESS FOR PRODUCING TRANSGLUTAMINASE | AJINOMOTO KK (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7972829-B2 | Process for producing transglutaminase | AJINOMOTO CO., INC. (JP) | 2011-07-05 | — | — | US | disclosed |
| US-7723067-B2 | Process for producing transglutaminase | AJINOMOTO CO., INC. (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-1219713-A1 | PROCESS FOR PRODUCING TRANSGLUTAMINASE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |