Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734544 | 1.00 | ALDH1A1 (0.44) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5735392 | 0.84 | ALDH1A1 (0.42) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5735391 | 0.84 | ALDH1A1 (0.42) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5735373 | 0.82 | FOLH1 (0.42) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5735371 | 0.82 | FOLH1 (0.42) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL27486689 | 0.81 | ALDH1A1 (0.44) | ALDH1A1NAAATSHRHTR2CFABP7 | |
| SCHEMBL5735745 | 0.80 | ELANE (0.38) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5735748 | 0.80 | ELANE (0.38) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5736762 | 0.78 | FKBP1A (0.38) | ALDH1A1FOLH1NAAATSHRHTR2C | |
| SCHEMBL5736768 | 0.78 | FKBP1A (0.38) | ALDH1A1FOLH1NAAATSHRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933379-B1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-6319902-B1 | TO ACTIVATE THE CENTRAL NERVOUS SYSTEM, SUCH AS, FOR EXAMPLE, SUSTAINED ACETYLCHOLINE RELEASING ACTION, ANTI-RESERPINE ACTION AND LOCOMOTOR INCREMENT | SHIONOGI & CO., LTD. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0933379-A1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |