Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 5/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787861 | 0.87 | SCN9A (0.47) | DPP4DPP8DPP9SCN9AACE | |
| SCHEMBL20787862 | 0.87 | SCN9A (0.47) | DPP4DPP8DPP9SCN9AACE | |
| SCHEMBL27503453 | 0.84 | F2 (0.46) | DPP4DPP8DPP9SCN9AACE | |
| SCHEMBL7870420 | 0.84 | F2 (0.46) | DPP4DPP8DPP9SCN9AACE | |
| SCHEMBL5735443 | 0.80 | REN (0.43) | DPP4DPP8DPP9SCN9AACE | |
| SCHEMBL5735435 | 0.80 | REN (0.43) | DPP4DPP8DPP9SCN9AACE | |
| SCHEMBL8250574 | 0.79 | DPP4 (0.54) | DPP4DPP8DPP9PREPDPP7 | |
| SCHEMBL3601946 | 0.78 | CTSL (0.51) | DPP4DPP8DPP9PREP | |
| SCHEMBL13444797 | 0.78 | DPP4 (0.50) | DPP4DPP8DPP9PREP | |
| SCHEMBL13463794 | 0.78 | DPP4 (0.50) | DPP4DPP8DPP9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933379-B1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-6319902-B1 | TO ACTIVATE THE CENTRAL NERVOUS SYSTEM, SUCH AS, FOR EXAMPLE, SUSTAINED ACETYLCHOLINE RELEASING ACTION, ANTI-RESERPINE ACTION AND LOCOMOTOR INCREMENT | SHIONOGI & CO., LTD. (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-0933379-A1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |