Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735435 | 1.00 | REN (0.43) | RENSCN9AACEDPP4DPP8 | |
| SCHEMBL7870420 | 0.86 | F2 (0.46) | SCN9AACEDPP4DPP8DPP9 | |
| SCHEMBL27503453 | 0.86 | F2 (0.46) | SCN9AACEDPP4DPP8DPP9 | |
| SCHEMBL20787861 | 0.83 | SCN9A (0.47) | SCN9AACEDPP4DPP8DPP9 | |
| SCHEMBL20787862 | 0.83 | SCN9A (0.47) | SCN9AACEDPP4DPP8DPP9 | |
| SCHEMBL5734956 | 0.80 | DPP4 (0.64) | SCN9AACEDPP4DPP8DPP9 | |
| SCHEMBL5736095 | 0.80 | ACE (0.51) | SCN9AACEF2PRSS1 | |
| Hydrochloric Acid SCHEMBL5735089 | 0.80 | DPP4 (0.60) | RENDPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5735095 | 0.80 | DPP4 (0.60) | RENDPP4DPP8DPP9 | |
| SCHEMBL5734100 | 0.77 | CMA1 (0.41) | SCN9AACEDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933379-B1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO (JP) | 2006-03-22 | — | — | EP | disclosed |
| EP-0933379-A1 | NOVEL PEPTIDE DERIVATIVES HAVING THIAZOLYL-ALANINE RESIDUE | SHIONOGI & CO., LTD. (JP) | 1999-08-04 | — | — | EP | disclosed |