Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20852085 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL26722615 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL4842055 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL239077 | 0.95 | — | — | |
| SCHEMBL752095 | 0.90 | — | — | |
| SCHEMBL5466115 | 0.88 | — | — | |
| SCHEMBL2705709 | 0.82 | PLG (0.43) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL25278103 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1013269 | 0.80 | MCL1 (0.39) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL1543551 | 0.80 | MCL1 (0.39) | ALDH1A1KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116083497-A | Synthesis method of sakubi qu intermediate | 南通常佑药业科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-112852768-B | Carbonyl reductase mutant and application thereof | 中国科学院天津工业生物技术研究所 | 2021-10-08 | — | — | CN | claimed |
| CN-112852768-A | Carbonyl reductase mutant and application thereof | 中国科学院天津工业生物技术研究所 | 2021-05-28 | — | — | CN | claimed |
| CN-107674026-B | Preparation method of ruxolitinib intermediate (3R) -3- (4-bromo-1H-pyrazol-1-yl) -cyclopentyl propionitrile | Haihua Life (Xiamen) Technology Co., Ltd. (CN) | 2019-12-06 | — | — | CN | claimed |
| CN-107674026-A | Luso replaces Buddhist nun's intermediate（3R) the preparation method of 3 (base of 4 bromine 1H pyrazoles 1) pentamethylene base propionitrile | 厦门海乐景生化有限公司 | 2018-02-09 | — | — | CN | claimed |
| CN-101723853-B | Method for synthesizing cyanoacetylene derivatives with one step | HANGZHOU ALLSINO CHEMICALS CO LTD | 2013-03-06 | — | — | CN | claimed |
| CN-101723853-A | Method for synthesizing cyanoacetylene derivatives with one step | HANGZHOU ALLSINO CHEMICALS CO | 2010-06-09 | — | — | CN | claimed |
| US-12551482-B2 | Aurora kinase inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2026-02-17 | — | — | US | disclosed |
| WO-2025081713-A1 | METHOD FOR PREPARING HYDRAZINE COMPOUND | 吉林凯莱英制药有限公司 | 2025-04-24 | — | — | WO | disclosed |
| CN-119060018-A | N, N-diaryl urea derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-118638755-A | Imine reductase mutant and preparation method of chiral hydrazine compound | 天津凯莱英生物科技有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118086417-A | Process for preparing hydrazines | 吉林凯莱英制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117070576-A | Process for preparing hydrazines | 吉林凯莱英制药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| US-6455559-B1 | Phenylacetamido-pyrazole derivatives, process for their preparation and their use as antitumor agents | PHARMACIA ITALIA S.P.A. (IT) | 2002-09-24 | — | — | US | disclosed |
| WO-2002048114-A1 | PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2002-06-20 | — | — | WO | disclosed |
| EP-0157260-B1 | 4,7-DIHYDROPYRAZOLO(3,4-B)PYRIDINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1990-06-13 | — | — | EP | disclosed |
| US-4873334-A | HYPOTENSIVE AGENTS, CORONARY VASODILATORS | SHIONOGI & CO., LTD. (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0157260-A1 | 4,7-Dihydropyrazolo(3,4-b)Pyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1985-10-09 | — | — | EP | disclosed |
| EP-0135252-A2 | Process for preparing 3-substituted-3-aminonitrile | ELI LILLY AND COMPANY (US) | 1985-03-27 | — | — | EP | disclosed |
| EP-0129408-A2 | (3-alkyl-5-isothiazolyl)ureas | ELI LILLY AND COMPANY (US) | 1984-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12551482-B2 | Aurora kinase inhibitors | MYC, AURKA, AURKC | ALDH1A1 4194/4885KMT2A 554/4885MEN1 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.