Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TOP1 | P11387 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952099 | 0.84 | ALDH1A1 (0.62) | ALDH1A1RORCTDP1KMT2AMEN1 | |
| SCHEMBL13238567 | 0.82 | TOP1 (0.74) | ALDH1A1TDP1KMT2AMEN1KDM4E | |
| SCHEMBL9391354 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTCYP1A2 | |
| SCHEMBL10890837 | 0.81 | RORC (0.68) | ALDH1A1RORCKMT2AMEN1HPGD | |
| SCHEMBL4785449 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL13763482 | 0.80 | TDP1 (0.70) | ALDH1A1RORCTDP1KMT2AMEN1 | |
| SCHEMBL10334083 | 0.80 | CFD (0.63) | ALDH1A1RORCTDP1KMT2AMEN1 | |
| SCHEMBL27295012 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1RORCTDP1KMT2AMEN1 | |
| SCHEMBL10334194 | 0.79 | SMN1; SMN2 (0.60) | ALDH1A1RORCTDP1KMT2AMEN1 | |
| SCHEMBL21649325 | 0.79 | ALDH1A1 (0.56) | ALDH1A1RORCTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189804-A1 | Synthetic method for the preparation of quinazolin-4-one derivative | BTG INTERNATIONAL LIMITED (GB) | 2006-08-24 | — | — | US | disclosed |
| EP-1675831-A2 | SYNTHETIC METHOD FOR THE PREPARATION OF QUINAZOLIN-4-ONE DERIVATIVES | BTG INTERNATIONAL LIMITED (GB) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005012260-A2 | SYNTHETIC METHOD FOR THE PREPARATION OF QUINAZOLIN-4-ONE DERIVATIVE | BTG INTERNATIONAL LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |
| EP-0114734-B1 | PYRIDINYLMETHYLAMINO-ARYLIC ACIDS | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |
| US-4568763-A | Process for producing N-acyl-acyloxy aromatic amines | CELANESE CORPORATION (US) | 1986-02-04 | — | — | US | disclosed |
| EP-0168908-A1 | Process for producing N-acyl-acyloxy aromatic amines | CELANESE CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4486593-A | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0114734-A2 | Pyridinylmethylamino-arylic acids | THE UPJOHN COMPANY (US) | 1984-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189804-A1 | Synthetic method for the preparation of quinazolin-4-one derivative | CYP4F3, CYP3A4, CYP4F11 | ALDH1A1 2145/4885RORC 2396/4885TDP1 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.