Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 11/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | CDC42 | P60953 | 1/20 | 0.37 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5734475 | 0.87 | MAOA (0.40) | MAOAADRA1AELANEPTGS2PTGS1 | |
| SCHEMBL3153668 | 0.77 | MAOA (0.37) | MAOAADRA1AELANETSHR | |
| SCHEMBL5735947 | 0.75 | GAA (0.55) | ELANE | |
| SCHEMBL4134433 | 0.75 | MAOA (0.61) | MAOAADRA1AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL11653626 | 0.74 | ELANE (0.48) | ELANE | |
| SCHEMBL6782970 | 0.73 | MAOA (0.56) | MAOAADRA1AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL11637941 | 0.73 | MAOA (0.50) | MAOAADRA1AAKR1C3AKR1C2PTGS1 | |
| SCHEMBL11639504 | 0.72 | MAOA (0.49) | MAOAADRA1AAKR1C3AKR1C2PTGS2 | |
| SCHEMBL9706321 | 0.72 | MAOA (0.79) | MAOAADRA1APTGS2TSHR | |
| Flunoxaprofen SCHEMBL25196 | 0.72 | MAOA (0.78) | MAOAADRA1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1686128-A2 | Isothiazole derivatives and their use as pesticides | Syngenta Limited (GB) | 2006-08-02 | — | — | EP | disclosed |
| EP-1265892-B1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LTD (GB) | 2006-01-18 | — | — | EP | disclosed |
| US-6703347-B2 | INSECTICIDES, FUNGICIDES, NEMATOCIDES, MOLLUSCICIDES, AND MITICIDES FOR PLANTS | SYNGENTA LIMITED (GB) | 2004-03-09 | — | — | US | disclosed |
| US-20030207926-A1 | Isothiazole derivatives and their use as pesticides | SYNGENTA LIMITED (GB) | 2003-11-06 | — | — | US | disclosed |
| EP-1265892-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | Syngenta Limited (GB) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001055144-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207926-A1 | Isothiazole derivatives and their use as pesticides | CBR1, CBR3, CYP1B1 | MAOA 2339/4885ADRA1A 370/4885ELANE 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.