⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31008552 | 1.00 | — | — | |
| SCHEMBL3761271 | 0.78 | AOC3 (0.38) | — | |
| SCHEMBL30561235 | 0.78 | — | — | |
| SCHEMBL16037977 | 0.77 | CDK1 (0.37) | — | |
| SCHEMBL9965937 | 0.74 | — | — | |
| SCHEMBL18838245 | 0.74 | CYP17A1 (0.42) | — | |
| SCHEMBL28801532 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL25403015 | 0.73 | — | — | |
| SCHEMBL9779753 | 0.73 | — | — | |
| SCHEMBL527555 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026101698-A1 | HEPCIDIN MIMETIC COMPOUNDS AND USES THEREOF | PROTAGONIST THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| WO-2022234271-A1 | HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |
| EP-3402785-B1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-20170197971-A1 | 3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-13 | — | — | US | disclosed |
| CN-104203952-B | Imidazo pyrrolidone-2 compounds | 诺华股份有限公司 | 2016-10-19 | — | — | CN | disclosed |
| CN-105120864-A | 2-aminopyrimidin-6-ones and analogs exhibiting anti-cancer and anti-proliferative activity | DECIPHERA PHARMACEUTICALS LLC | 2015-12-02 | — | — | CN | disclosed |
| US-20140170110-A1 | PYRIDIN-2(1H)-ONE DERIVATIVES USEFUL AS MEDICAMENTS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISORDERS, TRANSPLANT REJECTION, IMMUNE-MEDIATED AND INFLAMMATORY DISEASES | ALMIRALL, S.A. (ES) | 2014-06-19 | — | — | US | disclosed |
| CN-103649085-A | Pyridin-2(1h)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases | ALMIRALL SA | 2014-03-19 | — | — | CN | disclosed |
| WO-2012160030-A1 | PYRIDIN-2 (1H) -ONE DERIVATIVES USEFUL AS MEDICAMENTS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISORDERS, TRANSPLANT REJECTION, IMMUNE-MEDIATED AND INFLAMMATORY DISEASES | ALMIRALL, S.A. (ES) | 2012-11-29 | — | — | WO | disclosed |
| US-20060189613-A1 | Sulphonamide Compounds that Modulate Chemokine Receptor Activity (CCR4) | ASTRAZENECA AB (SE) | 2006-08-24 | — | — | US | disclosed |
| EP-1633723-A1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | AstraZeneca AB (SE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004108690-A1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | disclosed |
| EP-0039037-B1 | PYRIMIDYLTHIO-UREAS, MEDICINES CONTAINING THEM AND THEIR USE | Beiersdorf Aktiengesellschaft (DE) | 1985-01-16 | — | — | EP | disclosed |
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |
| EP-0039037-A1 | Pyrimidylthio-ureas, medicines containing them and their use | Beiersdorf Aktiengesellschaft (DE) | 1981-11-04 | — | — | EP | disclosed |