Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28818784 | 0.75 | AR (0.35) | ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL28064354 | 0.74 | P2RX3 (0.38) | ALDH1A1KDM4EGLAGAATDP1 | |
| SCHEMBL5735866 | 0.74 | — | — | |
| SCHEMBL31008552 | 0.74 | — | — | |
| SCHEMBL907751 | 0.73 | TNFSF11 (0.41) | ALDH1A1KDM4EGLAGAATDP1 | |
| SCHEMBL28042623 | 0.71 | CYP4F2 (0.36) | ALDH1A1KDM4EGLAGAANNMT | |
| SCHEMBL27956187 | 0.71 | HTT (0.37) | ALDH1A1KDM4EGLAMAPTKMT2A | |
| SCHEMBL3761271 | 0.71 | AOC3 (0.38) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL27670976 | 0.70 | KDM4E (0.43) | ALDH1A1KDM4ETDP1KMT2AALOX5 | |
| SCHEMBL24260245 | 0.69 | PRKCQ (0.38) | ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947292-A | nitrogen-containing heteroaryl compounds | HOFFMANN LA ROCHE | 2013-02-27 | — | — | CN | disclosed |