Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16528761 | 0.95 | DRD2 (0.61) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL8765703 | 0.93 | DRD2 (0.60) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL25197061 | 0.91 | DRD2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL661821 | 0.91 | DRD2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| Butylbenzyl SCHEMBL28097889 | 0.88 | CNR2 (0.55) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL6910779 | 0.87 | FFAR1 (0.60) | DRD2DRD4DRD3ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL8053906 | 0.87 | DRD2 (0.70) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL27260337 | 0.86 | FFAR1 (0.54) | DRD2DRD4DRD3FFAR1MAOA | |
| SCHEMBL6912529 | 0.85 | DRD2 (0.49) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL10479366 | 0.83 | DRD2 (0.63) | DRD2DRD4DRD3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 608 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | claimed |
| CN-108472220-B | Reducing the perception of skin stinging | 西姆莱斯股份公司 | 2022-06-17 | — | — | CN | claimed |
| EP-3373895-B1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2020-08-19 | — | — | EP | claimed |
| CN-104414869-B | A kind of skin and/or hair whitening mixture | 西姆莱斯股份公司 | 2019-09-03 | — | — | CN | claimed |
| EP-3373895-A1 | REDUCTION OF STINGING SENSATION ON SKIN | Symrise AG (DE) | 2018-09-19 | — | — | EP | claimed |
| CN-108472220-A | Reduce skin irritation impression | 西姆莱斯股份公司 | 2018-08-31 | — | — | CN | claimed |
| EP-2842607-B1 | A skin and/or hair whitening mixture | SYMRISE AG (DE) | 2018-05-30 | — | — | EP | claimed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | claimed |
| CN-104414869-A | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG | 2015-03-18 | — | — | CN | claimed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | claimed |
| EP-1879457-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | Ciba Specialty Chemicals Holding, Inc. (CH) | 2008-01-23 | — | — | EP | claimed |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | CIBA SPECIALTY CHEMICALS CORP. | 2007-10-04 | — | — | US | claimed |
| EP-1755381-A2 | ANTIMICROBIAL SILICON OXIDE FLAKES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-02-28 | — | — | EP | claimed |
| WO-2006120135-A1 | ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-11-16 | — | — | WO | claimed |
| US-20060040847-A1 | Hard surface treating compositions | RECKITT BENCKISER INC. | 2006-02-23 | — | — | US | claimed |
| WO-2005107456-A2 | ANTIMICROBIAL SILICON OXIDE FLAKES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-11-17 | — | — | WO | claimed |
| EP-1537201-A1 | HARD SURFACE TREATING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2005-06-08 | — | — | EP | claimed |
| EP-0805672-B1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 2004-08-25 | — | — | EP | claimed |
| WO-2004024861-A1 | HARD SURFACE TREATING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2004-03-25 | — | — | WO | claimed |
| US-5665333-A | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth | PROVSEAL LLC | 1997-09-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | STING1, TYR, CUTA | DRD2 2146/4885DRD4 2316/4885DRD3 1906/4885 |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | TYR, AHR, CYP1B1 | DRD2 515/4885DRD4 434/4885DRD3 264/4885 |
| US-20070231295-A1 | Antimicrobial Silicon Oxide Flakes | SIK2, SIK3, SIK1 | DRD2 2600/4885DRD4 1907/4885DRD3 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.