Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16528761 | 0.98 | DRD2 (0.61) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL573713 | 0.93 | DRD2 (0.63) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL25197061 | 0.88 | DRD2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL661821 | 0.88 | DRD2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| Butylbenzyl SCHEMBL28097889 | 0.88 | CNR2 (0.55) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL10367030 | 0.87 | CNR2 (0.59) | FFAR1CNR1CNR2PLA2G4BNAAA | |
| SCHEMBL16902832 | 0.86 | CHRNB2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL9009814 | 0.86 | CHRNB2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL16902831 | 0.86 | CHRNB2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A | |
| SCHEMBL16902829 | 0.86 | CHRNB2 (0.65) | DRD2DRD4DRD3ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | claimed |
| CN-108472220-B | Reducing the perception of skin stinging | 西姆莱斯股份公司 | 2022-06-17 | — | — | CN | claimed |
| EP-3373895-B1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2020-08-19 | — | — | EP | claimed |
| EP-3373895-A1 | REDUCTION OF STINGING SENSATION ON SKIN | Symrise AG (DE) | 2018-09-19 | — | — | EP | claimed |
| EP-2842607-B1 | A skin and/or hair whitening mixture | SYMRISE AG (DE) | 2018-05-30 | — | — | EP | claimed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | claimed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | claimed |
| EP-2842607-A1 | A skin and/or hair whitening mixture | Symrise AG (DE) | 2015-03-04 | — | — | EP | claimed |
| CN-119345088-A | Whitening nanoemulsion and preparation method thereof | 广东鼎尖国际生物科技有限公司 | 2025-01-24 | — | — | CN | disclosed |
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | disclosed |
| EP-4401843-A1 | SOLID CLEANSING COMPOSITIONS AND METHODS FOR THE SAME | Colgate-Palmolive Company (US) | 2024-07-24 | — | — | EP | disclosed |
| WO-2023043703-A1 | SOLID CLEANSING COMPOSITIONS AND METHODS FOR THE SAME | COLGATE-PALMOLIVE COMPANY (US) | 2023-03-23 | — | — | WO | disclosed |
| US-20230079706-A1 | Solid Cleansing Compositions and Methods for the Same | COLGATE-PALMOLIVE COMPANY (US) | 2023-03-16 | — | — | US | disclosed |
| CN-108472220-B | Reducing the perception of skin stinging | 西姆莱斯股份公司 | 2022-06-17 | — | — | CN | disclosed |
| WO-2018001485-A1 | MEDICAMENT AND COSMETIC COMPOSITION COMPRISING RESORCINOL DERIVATIVES | SYMRISE AG (DE) | 2018-01-04 | — | — | WO | disclosed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | disclosed |
| CN-104414869-A | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG | 2015-03-18 | — | — | CN | disclosed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | disclosed |
| EP-2842607-A1 | A skin and/or hair whitening mixture | Symrise AG (DE) | 2015-03-04 | — | — | EP | disclosed |
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | STING1, TYR, CUTA | DRD2 2146/4885DRD4 2316/4885DRD3 1906/4885 |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | TYR, AHR, CYP1B1 | DRD2 515/4885DRD4 434/4885DRD3 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.