Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5737779 | 0.89 | CCR4 (0.61) | CCR4 | |
| SCHEMBL5957166 | 0.77 | CCR4 (0.64) | CCR4 | |
| SCHEMBL5737239 | 0.77 | CCR4 (0.38) | CCR4 | |
| SCHEMBL5748366 | 0.76 | CCR4 (0.65) | CCR4 | |
| SCHEMBL5617350 | 0.71 | CCR5 (0.61) | CCR4 | |
| SCHEMBL5748169 | 0.70 | CCR4 (0.61) | CCR4 | |
| SCHEMBL1731814 | 0.69 | CCR4 (1.00) | CCR4 | |
| SCHEMBL6848031 | 0.69 | CCR4 (0.80) | CCR4 | |
| SCHEMBL6848036 | 0.69 | CCR4 (0.79) | CCR4 | |
| SCHEMBL1966740 | 0.69 | CCR4 (1.00) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633723-A1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | AstraZeneca AB (SE) | 2006-03-15 | — | — | EP | claimed |
| WO-2004108690-A1 | SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4) | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | WO | claimed |