Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657740 | 0.87 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL6714485 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL10750177 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL9440112 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL7907147 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL1422341 | 0.81 | KDM4E (0.56) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL3555520 | 0.79 | KDM4E (0.59) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL7847086 | 0.78 | HPGD (0.66) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL20541797 | 0.77 | GRIN1 (0.56) | ALDH1A1KDM4ELMNAHPGDHTT | |
| SCHEMBL8864614 | 0.77 | CYP4F2 (0.60) | ALDH1A1KDM4ELMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141570-B2 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY (US) | 2006-11-28 | — | — | US | disclosed |
| EP-1565186-B1 | N-(4-(PIPERAZIN-1-YL)-PHENYL-2-OXAZOLIDINONE-5-CARBOXAMIDE DERIVATES AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20040167357-A1 | Compounds and methods for preparing methanesulfonamides | PHARMACIA & UPJOHN COMPANY | 2004-08-26 | — | — | US | disclosed |
| US-20040142939-A1 | N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142939-A1 | N-Aryl-2-oxazolidinone-5-carboxamides and their derivatives | OXA1L, AADAC, MT-ND5 | ALDH1A1 678/4885KDM4E 1085/4885LMNA 3224/4885 |
| US-20040167357-A1 | Compounds and methods for preparing methanesulfonamides | HACL2, RABL6, FARS2 | ALDH1A1 660/4885KDM4E 1560/4885LMNA 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.