SCHEMBL5738243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29417758	0.86	SMN1; SMN2 (0.50)	LMNASMN1; SMN2SRPK1KDM4ECYP1A2
	SCHEMBL15101008	0.86	SMN1; SMN2 (0.50)	LMNASMN1; SMN2SRPK1KDM4ECYP1A2
	SCHEMBL19582507	0.85	SMN1; SMN2 (0.49)	LMNASMN1; SMN2SRPK1KDM4ECYP1A2
	SCHEMBL25639667	0.85	SMN1; SMN2 (0.47)	LMNASMN1; SMN2ALDH1A1HRH3
	SCHEMBL15093911	0.82	LMNA (0.66)	LMNASMN1; SMN2KDM4ETSHRHSD17B10
	SCHEMBL18914793	0.82	LMNA (0.47)	LMNASMN1; SMN2ADRB2KDM4EHSD17B10
	SCHEMBL20503423	0.82	ADRB2 (0.54)	LMNASMN1; SMN2ADRB2HTR1AHTR2C
	SCHEMBL29417642	0.82	LMNA (0.47)	LMNASMN1; SMN2ADRB2KDM4EHSD17B10
	SCHEMBL20566963	0.82	HRH3 (0.56)	LMNASMN1; SMN2ALDH1A1HTR6DRD2
	SCHEMBL20503432	0.82	LMNA (0.45)	LMNASMN1; SMN2CYP2D6TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.