Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | PGR | P06401 | 1/20 | 0.76 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | MGLL | Q99685 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | CNR1 | P21554 | 3/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | FAAH | O00519 | 3/20 | 0.65 |
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810935 | 1.00 | ALDH1A1 (0.77) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL5738380 | 1.00 | ALDH1A1 (0.77) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL7796369 | 1.00 | ALDH1A1 (0.77) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL24209 | 0.98 | NR1I2 (0.78) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL24208 | 0.98 | NR1I2 (0.78) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL4807962 | 0.98 | NR1I2 (0.78) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL31264367 | 0.98 | NR1I2 (0.78) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL20582487 | 0.98 | NR1I2 (0.78) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL20582488 | 0.98 | NR1I2 (0.78) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 | |
| SCHEMBL6808635 | 0.97 | ALDH1A1 (0.82) | ALDH1A1CYP3A4ALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436047-B2 | Preventive or ameliorating agent for liver disease involving hepatopathy | SUNTORY HOLDINGS LIMITED (JP) | 2013-05-07 | — | — | US | disclosed |
| EP-1707198-B1 | PREVENTIVE OR AMELIORATING AGENT FOR LIVER DISEASE INVOLVING HEPATOPATHY | SUNTORY HOLDINGS LTD (JP) | 2012-12-19 | — | — | EP | disclosed |
| CN-1842329-B | Preventive or ameliorating agent for liver disease involving hepatopathy | SUNTORY HOLDINGS LTD | 2011-09-14 | — | — | CN | disclosed |
| EP-1707198-A1 | PREVENTIVE OR AMELIORATING AGENT FOR LIVER DISEASE INVOLVING HEPATOPATHY | SUNTORY LIMITED (JP) | 2006-10-04 | — | — | EP | disclosed |
| CN-1842329-A | Preventive or ameliorating agent for liver disease involving hepatopathy | SUNTORY LTD (JP) | 2006-10-04 | — | — | CN | disclosed |
| US-20060217442-A1 | Preventive or ameliorating agent for liver disease involving hepatopathy | SUNTORY LIMITED (JP) | 2006-09-28 | — | — | US | disclosed |
| EP-0790056-B1 | USE OF COMPOSITION FOR PREVENTING OR TREATING DISEASES CAUSED BY ABNORMALITIES IN CARTILAGE TISSUES | SUNTORY LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6765020-B2 | ADMINISTERING 6,9- OCTADECADIENOIC ACID, 8,11-EICOSADIENOIC ACID AND/OR 5,8,11- EICOSATRIENOIC ACID | SUNTORY LIMITED (JP) | 2004-07-20 | — | — | US | disclosed |
| US-20020012690-A1 | DRUGS FOR PREVENTION AND TREATMENT OF DISEASES CAUSED BY ABNORMALITIES IN CARTILAGE TISSUES | SUNTORY HOLDINGS LTD. (JP) | 2002-01-31 | — | — | US | disclosed |
| EP-0790056-A1 | PREVENTIVE OR REMEDY FOR DISEASES CAUSED BY ABNORMALITIES IN CARTILAGE TISSUES | SUNTORY LIMITED (JP) | 1997-08-20 | — | — | EP | disclosed |