Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | PGR | P06401 | 1/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | MGLL | Q99685 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | FAAH | O00519 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24209 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL4807962 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL31264367 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL20582488 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL20582487 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL6810935 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL7796369 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL5738380 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL5738375 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL29655825 | 0.98 | NR1I2 (0.76) | NR1I2PGRADORA3PTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 794 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213516-A1 | Prophylactic Methods For Treating ALS | BIOJIVA LLC | 2025-07-03 | — | — | US | claimed |
| EP-4522147-A1 | THERAPEUTIC METHODS FOR TREATING ALS | Biojiva LLC (US) | 2025-03-19 | — | — | EP | claimed |
| EP-4499061-A1 | PROPHYLACTIC METHODS FOR TREATING ALS | Biojiva LLC (US) | 2025-02-05 | — | — | EP | claimed |
| CN-119286673-A | Bacillus amyloliquefaciens for improving soy sauce color, inhibiting bacteria and enhancing aroma and application thereof | 天津科技大学 | 2025-01-10 | — | — | CN | claimed |
| CN-118813730-A | Preparation method of glyceride type polyunsaturated fatty acid | 浙江医药股份有限公司新昌制药厂 | 2024-10-22 | — | — | CN | claimed |
| US-12109194-B2 | Synergistic combination therapy for treating ALS | BIOJIVA LLC (US) | 2024-10-08 | — | — | US | claimed |
| US-20240216322-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASE | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2024-07-04 | — | — | US | claimed |
| CN-117264670-B | Diesel antiwear agent and preparation method thereof | 湖南浩润科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117264670-A | Diesel antiwear agent and preparation method thereof | 湖南浩润科技有限公司 | 2023-12-22 | — | — | CN | claimed |
| WO-2023220058-A1 | THERAPEUTIC METHODS FOR TREATING ALS | RETROTOPE, INC. (US) | 2023-11-16 | — | — | WO | claimed |
| US-20110218243-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASE | AMARIN PHARMA, INC. (US) | 2011-09-08 | — | — | US | claimed |
| US-20110034555-A1 | COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES WITHOUT RAISING LDL-C LEVELS IN A SUBJECT ON CONCOMITANT STATIN THERAPY | AMARIN PHARMA , INC. (US) | 2011-02-10 | — | — | US | claimed |
| WO-2010147994-A1 | COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES WITHOUT RAISING LDL-C LEVELS IN A SUBJECT ON CONCOMITANT STATIN THERAPY | AMARIN PHARMA, INC. (US) | 2010-12-23 | — | — | WO | claimed |
| CN-101796014-A | Production and purification of esters of polyunsaturated fatty acids | MARTEK BIOSCIENCES CORP | 2010-08-04 | — | — | CN | claimed |
| US-20070207503-A1 | DETECTION OF ALCOHOL-ESTERIFIED FATTY ACIDS | DETROIT R&D | 2007-09-06 | — | — | US | claimed |
| WO-2006083434-A1 | USE OF ARACHIDONIC ACID AND ITS DERIVATIVES FOR INCREASING SKELETAL MUSCLE MASS | LLEWELLYN WILLIAM C (US) | 2006-08-10 | — | — | WO | claimed |
| US-20050137256-A1 | Use of arachidonic acid as a method of increasing skeletal muscle mass | LLEWELLYN WILLIAM C (US) | 2005-06-23 | — | — | US | claimed |
| US-20010041365-A1 | Methods for monitoring alcohol consumption | GENERAL HOSPITAL CORPORATION, THE | 2001-11-15 | — | — | US | claimed |
| US-5411751-A | Enteric administering nutrients with medium chain fatty acids to protect intestines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-05-02 | — | — | US | claimed |
| WO-1993020717-A2 | REDUCING GASTROINTESTINAL IRRITATION IN INFANT NUTRITION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-10-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250213516-A1 | Prophylactic Methods For Treating ALS | ALOX12, ALOX15B, ALOX15 | NR1I2 3917/4885PGR 3206/4885ADORA3 1563/4885 |
| US-12109194-B2 | Synergistic combination therapy for treating ALS | SMN1; SMN2, ALOX12, ALOX15 | NR1I2 1971/4885PGR 2224/4885ADORA3 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.