Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | PGR | P06401 | 1/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | MGLL | Q99685 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | FAAH | O00519 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24209 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL4807962 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL24208 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL20582488 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL20582487 | 1.00 | NR1I2 (0.78) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL6810935 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL7796369 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL5738380 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL5738375 | 0.98 | ALDH1A1 (0.77) | NR1I2PGRADORA3PTGS2PDE4D | |
| SCHEMBL29655825 | 0.98 | NR1I2 (0.76) | NR1I2PGRADORA3PTGS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720051-A1 | IONIZABLE LIPIDS | Bristol-Myers Squibb Company (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-3335140-B1 | SYSTEMS, APPARATUS, AND METHODS FOR ANALYZING AND PREDICTING CELLULAR PATHWAYS | MASSACHUSETTS INST TECHNOLOGY (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20240390284-A1 | IONIZABLE LIPIDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-11-28 | — | — | US | disclosed |
| WO-2024243480-A1 | IONIZABLE LIPIDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240390284-A1 | IONIZABLE LIPIDS | NPC1L1, ABCB4, NPC1 | NR1I2 2550/4885PGR 1267/4885ADORA3 3882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.