Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39835 | 0.84 | TAAR1 (0.56) | MAOBCES2MEN1KMT2AALDH1A1 | |
| SCHEMBL30093723 | 0.84 | CES2 (0.71) | MAOBCES2MEN1KMT2AALDH1A1 | |
| SCHEMBL39834 | 0.84 | CES2 (0.71) | MAOBCES2MEN1KMT2AALDH1A1 | |
| SCHEMBL12253688 | 0.83 | MAOB (0.50) | MAOBMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL13377016 | 0.79 | DAO (0.50) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL10612843 | 0.77 | CES2 (0.56) | MAOBCES2MEN1KMT2AALDH1A1 | |
| SCHEMBL2610304 | 0.77 | MAOB (0.67) | MAOBCES2MEN1KMT2AHTT | |
| Acetoacetic Acid SCHEMBL27759778 | 0.77 | CES2 (0.56) | MAOBCES2MEN1KMT2AALDH1A1 | |
| Toluene SCHEMBL27952197 | 0.76 | MEN1 (0.61) | MAOBCES2MEN1KMT2AALDH1A1 | |
| SCHEMBL6789638 | 0.75 | MAOB (0.48) | MAOBMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |