Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39835 | 0.93 | TAAR1 (0.56) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL3237564 | 0.85 | TAAR1 (0.64) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL16398826 | 0.83 | MAOB (0.50) | ACP3TAAR1IDO1HTR2AHTR2C | |
| SCHEMBL17508140 | 0.81 | LTA4H (0.50) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL30644998 | 0.81 | DAO (0.49) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL18001841 | 0.81 | DAO (0.49) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL7435425 | 0.80 | TAAR1 (0.58) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL30370514 | 0.80 | TAAR1 (0.58) | DAOACP3TAAR1IDO1HTR2A | |
| SCHEMBL13403379 | 0.79 | ALDH1A1 (0.53) | IDO1MAPTPOLBLTA4HKDM4E | |
| SCHEMBL5738726 | 0.79 | MAOB (0.62) | ACP3MAPTPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881967-B1 | SUBSTITUTED BENZO(D)ISOXAZOL-3-YL AMINE COMPOUNDS AS ANALGESICS | GRUENENTHAL GMBH (DE) | 2010-04-28 | — | — | EP | disclosed |