Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716099 | 0.88 | FPR2 (0.55) | KMT2AALDH1A1FPR2PROKR1POLB | |
| SCHEMBL6311243 | 0.87 | ALDH1A1 (0.56) | KMT2AALDH1A1POLBLMNANPSR1 | |
| SCHEMBL28840734 | 0.85 | FPR2 (0.55) | KMT2AALDH1A1FPR2PROKR1POLB | |
| SCHEMBL2761098 | 0.83 | FPR2 (0.57) | KMT2AALDH1A1FPR2PROKR1POLB | |
| SCHEMBL15537227 | 0.80 | HRH2 (0.44) | KMT2AALDH1A1FPR2PROKR1POLB | |
| SCHEMBL9876055 | 0.78 | KMT2A (0.59) | KMT2AALDH1A1POLBLMNAMEN1 | |
| SCHEMBL6627953 | 0.76 | ALDH1A1 (0.70) | KMT2AALDH1A1POLBLMNANPSR1 | |
| SCHEMBL6311126 | 0.76 | POLB (0.54) | KMT2AALDH1A1POLBLMNAMEN1 | |
| SCHEMBL1980907 | 0.75 | HRH2 (0.46) | KMT2AALDH1A1FPR2PROKR1LMNA | |
| SCHEMBL3718479 | 0.75 | KDM4E (0.64) | KMT2AALDH1A1POLBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615899-A1 | ALPHA-SUBSTITUTED CARBOXYLIC ACIDS AS PPAR MODULATORS | PFIZER INC. (US) | 2006-01-18 | — | — | EP | disclosed |
| US-20050234066-A1 | Alpha substituted carboxylic acids | AGOURON PHARMACEUTICALS, INC. | 2005-10-20 | — | — | US | disclosed |
| US-20050187266-A1 | Alpha substituted carboxylic acids | PFIZER INC | 2005-08-25 | — | — | US | disclosed |
| WO-2004092145-A1 | ALPHA SUBSTITUTED CARBOXYLIC ACID AS PPAR MODULATORS | PFIZER INC. (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234066-A1 | Alpha substituted carboxylic acids | PPARG, PPARA, PPARD | KMT2A 2478/4885ALDH1A1 177/4885FPR2 809/4885 |
| US-20050187266-A1 | Alpha substituted carboxylic acids | PPARG, PPARA, PPARD | KMT2A 2478/4885ALDH1A1 177/4885FPR2 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.