Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893414 | 0.79 | HTR1A (0.77) | HTR1A | |
| SCHEMBL4239985 | 0.78 | DRD2 (0.50) | HTR1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL4239981 | 0.78 | DRD2 (0.50) | HTR1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL4245221 | 0.76 | DRD2 (0.53) | HTR1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL4245225 | 0.76 | DRD2 (0.53) | HTR1AKMT2AKDM4EALDH1A1 | |
| SCHEMBL4879734 | 0.76 | HTR1A (0.75) | HTR1A | |
| SCHEMBL13879532 | 0.74 | KMT2A (0.77) | KMT2AALDH1A1 | |
| SCHEMBL22813625 | 0.72 | HRH3 (0.83) | HTR1AHRH3SIGMAR1 | |
| SCHEMBL5739138 | 0.71 | SMN1; SMN2 (0.63) | HTR1AKMT2AKDM4EALDH1A1RECQL | |
| SCHEMBL8801774 | 0.71 | NR1H2 (0.62) | HTR1AKMT2AKDM4EALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244670-B1 | HYDANTOIN DERIVATIVE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USING SAME | MGI GP INC (US) | 2006-03-08 | — | — | EP | claimed |
| EP-1244670-B1 | HYDANTOIN DERIVATIVE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USING SAME | MGI GP INC (US) | 2006-03-08 | — | — | EP | disclosed |