Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6090931 | 0.86 | KMT2A (0.58) | MAPTTP53ALOX15TSHRKMT2A | |
| SCHEMBL6091187 | 0.81 | SERPINE1 (0.44) | SERPINE1CYP3A4ALOX15HSD17B10MAPK8 | |
| SCHEMBL27621758 | 0.80 | HDAC1 (0.50) | ACLYMAPTTP53MEN1CYP3A4 | |
| SCHEMBL14117729 | 0.79 | SERPINE1 (0.56) | ACLYSERPINE1MAPTMEN1CYP3A4 | |
| SCHEMBL6089927 | 0.79 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8687160 | 0.77 | ACLY (0.62) | ACLYKMT2AMAPK8EDNRA | |
| SCHEMBL6093339 | 0.76 | SERPINE1 (0.61) | ACLYSERPINE1MAPTMEN1CYP3A4 | |
| SCHEMBL4709825 | 0.73 | MAPK8 (0.79) | MAPK8 | |
| SCHEMBL27658626 | 0.73 | MEN1 (0.61) | SERPINE1MAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL6092353 | 0.72 | SERPINE1 (0.56) | ACLYSERPINE1MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |