Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6091187 | 0.80 | SERPINE1 (0.44) | EDNRAEDNRB | |
| SCHEMBL5739485 | 0.79 | ACLY (0.53) | EDNRAEDNRB | |
| SCHEMBL8902174 | 0.71 | EDNRB (0.76) | EDNRAEDNRB | |
| SCHEMBL8900846 | 0.71 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL8856802 | 0.71 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL6092056 | 0.70 | EDNRA (0.47) | EDNRAEDNRB | |
| SCHEMBL8857250 | 0.69 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL8902335 | 0.69 | EDNRB (0.80) | EDNRAEDNRB | |
| SCHEMBL6090219 | 0.69 | KMT2A (0.54) | — | |
| SCHEMBL7397513 | 0.69 | HDAC1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | EDNRA 155/4885EDNRB 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.