Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729659 | 0.87 | KMT2A (0.56) | KMT2AMAPK8ALDH1A1CYP1A2HPGD | |
| SCHEMBL5739485 | 0.86 | ACLY (0.53) | KMT2AMAPK8MAPTLMNATP53 | |
| SCHEMBL6090219 | 0.83 | KMT2A (0.54) | KMT2AMAPK8ALDH1A1CYP1A2HPGD | |
| SCHEMBL5746891 | 0.82 | KMT2A (0.52) | KMT2AMAPK8ALDH1A1HPGDPLA2G2A | |
| SCHEMBL11730958 | 0.82 | ALDH1A1 (0.51) | KMT2AMAPK8ALDH1A1CYP1A2HPGD | |
| SCHEMBL1504118 | 0.78 | MAPT (0.55) | KMT2AALDH1A1HPGDMDM2MAPT | |
| SCHEMBL4886339 | 0.77 | PLA2G2A (0.55) | KMT2AMAPK8MDM2PLA2G2AMAPT | |
| SCHEMBL22005111 | 0.76 | MAPK8 (0.56) | KMT2AMAPK8ALDH1A1PLA2G2AMAPT | |
| SCHEMBL11263827 | 0.76 | KMT2A (0.60) | KMT2APLA2G2ASMN1; SMN2 | |
| SCHEMBL5172795 | 0.75 | KMT2A (0.50) | KMT2AMAPK8HPGDMDM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160879-A1 | Indoles useful in the treatment of inflammation | IDO1, PTGS1, IDO2 | KMT2A 3542/4885MAPK8 3463/4885ALDH1A1 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.