SCHEMBL5739655

SCHEMBL5739655

COC(=CC=Cc1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
MAOB P27338 2/20 0.46
POLB P06746 1/20 0.45
PLA2G7 Q13093 1/20 0.42
TRPA1 O75762 3/20 0.42
GAA P10253 2/20 0.42
MAPK1 P28482 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
NFE2L2 Q16236 1/20 0.42
ALOX5 P09917 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5739654 1.00 LMNA (0.55) LMNAALDH1A1KDM4EHPGDCYP1A2
SCHEMBL3233505 0.79 MAOB (0.43) LMNAALDH1A1KDM4EHPGDCYP1A2
SCHEMBL28294771 0.78 LMNA (0.49) LMNAALDH1A1KDM4EHPGDCYP1A2
SCHEMBL819399 0.76 MEN1 (0.46) LMNAALDH1A1KDM4EHPGDCYP1A2
SCHEMBL713257 0.76 MEN1 (0.46) LMNAALDH1A1KDM4EHPGDCYP1A2
SCHEMBL5739717 0.76 KDM4E (0.60) LMNAALDH1A1KDM4EHPGDCYP2C9
SCHEMBL5739713 0.76 KDM4E (0.60) LMNAALDH1A1KDM4EHPGDCYP2C9
SCHEMBL23458229 0.75 MAOB (0.52) LMNAALDH1A1KDM4EHPGDCYP1A2
SCHEMBL16173951 0.75 TSHR (0.43) LMNAALDH1A1HPGDPOLBGAA
SCHEMBL11879098 0.75 TSHR (0.48) LMNAALDH1A1KDM4EHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487936-B1 NON-VISUALIZED PERMANENT INFORMATION RECORDING SUBSTRATE FOR USE AS SECURITY LABEL FOR AUTHENTICATION COUNCIL SCIENT IND RES (IN) 2006-09-06 EP claimed
US-6951692-B1 Fluorescent compounds dispersed in polymer films, and coated on metals, glass or polymer sheets having codes recorded by masking; counterfeiting prevention COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-04 US claimed
EP-1487936-A1 NON-VISUALIZED PERMANENT INFORMATION RECORDING SUBSTRATE FOR USE AS SECURITY LABEL FOR AUTHENTICATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-12-22 EP claimed
WO-2003080759-A1 NON-VISUALIZED PERMANENT INFORMATION RECORDING SUBSTRATE FOR USE AS SECURITY LABEL FOR AUTHENTICATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 WO claimed
EP-1487936-B1 NON-VISUALIZED PERMANENT INFORMATION RECORDING SUBSTRATE FOR USE AS SECURITY LABEL FOR AUTHENTICATION COUNCIL SCIENT IND RES (IN) 2006-09-06 EP disclosed
US-6951692-B1 Fluorescent compounds dispersed in polymer films, and coated on metals, glass or polymer sheets having codes recorded by masking; counterfeiting prevention COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-10-04 US disclosed
EP-1487936-A1 NON-VISUALIZED PERMANENT INFORMATION RECORDING SUBSTRATE FOR USE AS SECURITY LABEL FOR AUTHENTICATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-12-22 EP disclosed
WO-2003080759-A1 NON-VISUALIZED PERMANENT INFORMATION RECORDING SUBSTRATE FOR USE AS SECURITY LABEL FOR AUTHENTICATION COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 WO disclosed