SCHEMBL28294771

SCHEMBL28294771

O=C(CC(=O)OC(=CC=Cc1ccccc1)c1ccccc1)OC(=CC=Cc1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.49
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 3/20 0.48
POLB P06746 1/20 0.46
HPGD P15428 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
PLA2G7 Q13093 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5739654 0.78 LMNA (0.55) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL5739655 0.78 LMNA (0.55) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL3233505 0.72 MAOB (0.43) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL9116949 0.71 LMNA (0.57) LMNAALDH1A1CYP1A2CYP2C9NPC1
SCHEMBL5739713 0.70 KDM4E (0.60) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL5739717 0.70 KDM4E (0.60) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL4817475 0.69 AKR1C1 (0.60) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL1901012 0.69 AKR1C1 (0.60) LMNAALDH1A1KDM4EPOLBHPGD
SCHEMBL28084374 0.69 TSHR (0.41) KDM4EHPGDNPC1RAB9ASMN1; SMN2
SCHEMBL28759139 0.69 LMNA (0.56) LMNAALDH1A1KDM4EPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116546962-A Skin care composition 莱雅公司 2023-08-04 CN claimed
CN-109689012-B Photostable compositions and methods of use 莱雅公司 2022-05-31 CN claimed
CN-111971020-A Method for enhancing UVA photoprotection using antioxidants 莱雅公司 2020-11-20 CN claimed
CN-109689012-A Photostable compositions and methods of use 莱雅公司 2019-04-26 CN claimed
CN-117597102-A Sun protection W/O emulsion 莱雅公司 2024-02-23 CN disclosed
CN-111971020-B Methods for enhancing UVA photoprotection using antioxidants 莱雅公司 2024-01-02 CN disclosed
CN-113164335-B Mineral sunscreen compositions 欧莱雅 2023-11-14 CN disclosed
CN-116889525-A Sunscreen compositions based on small particle O/W emulsions 莱雅公司 2023-10-17 CN disclosed
CN-115697286-A Cosmetic composition containing a silicone resin combination capable of forming a multilayer structure after application to a keratinous material 莱雅公司 2023-02-03 CN disclosed
CN-114828804-A Sunscreen composition 莱雅公司 2022-07-29 CN disclosed
CN-114760974-A Powdery cosmetic composition 莱雅公司 2022-07-15 CN disclosed
CN-114746064-A Dual phase sunscreen composition 莱雅公司 2022-07-12 CN disclosed
CN-109689012-B Photostable compositions and methods of use 莱雅公司 2022-05-31 CN disclosed
CN-108367177-B High internal phase emulsion compositions for improving the SPF and rheology of the compositions 莱雅公司 2021-12-21 CN disclosed
CN-113164335-A Mineral sunscreen compositions 欧莱雅 2021-07-23 CN disclosed
CN-111971020-A Method for enhancing UVA photoprotection using antioxidants 莱雅公司 2020-11-20 CN disclosed
CN-111356504-A Dual phase sunscreen composition 莱雅公司 2020-06-30 CN disclosed
CN-110225743-A Microemulsion compositions comprising polydatin and methods of use 莱雅公司 2019-09-10 CN disclosed
CN-109689012-A Photostable compositions and methods of use 莱雅公司 2019-04-26 CN disclosed