Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206342 | 0.96 | DGAT1 (0.59) | DGAT1NR4A2ALDH1A1GAANPC1 | |
| SCHEMBL21839189 | 0.85 | SLC6A3 (0.51) | DGAT1NR4A2ALDH1A1GAANPC1 | |
| SCHEMBL30546048 | 0.82 | NR4A2 (0.51) | DGAT1NR4A2ALDH1A1GAANPC1 | |
| SCHEMBL1476688 | 0.82 | NR4A2 (0.51) | DGAT1NR4A2ALDH1A1GAANPC1 | |
| SCHEMBL29773857 | 0.80 | NR4A2 (0.56) | NR4A2ALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL4577829 | 0.80 | NR4A2 (0.56) | NR4A2ALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL23063802 | 0.79 | SLC6A3 (0.49) | DGAT1NR4A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31253108 | 0.79 | SLC6A3 (0.49) | DGAT1NR4A2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2365984 | 0.79 | NR4A2 (0.51) | NR4A2ALDH1A1GAARAB9AL3MBTL1 | |
| SCHEMBL5734786 | 0.79 | MAP2K1 (0.47) | ALDH1A1GAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |