SCHEMBL5740023

SCHEMBL5740023

C[Si](C)(C)OC1=C(O[Si](C)(C)C)CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11344260 0.93
SCHEMBL818161 0.83
SCHEMBL817005 0.81
SCHEMBL817354 0.77
SCHEMBL10339597 0.76 ALDH1A1 (0.32)
SCHEMBL1440006 0.75
SCHEMBL5253966 0.74
SCHEMBL14470739 0.73
SCHEMBL11072971 0.71 NOS1 (0.38)
SCHEMBL818171 0.71 SLC6A2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290464-A Preparation method of 1, 2-bis (trimethylsiloxy) cyclohexene 杭州鑫富科技有限公司 2024-07-05 CN claimed
EP-2516378-B1 SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION UNIV READING (GB) 2014-01-22 EP claimed
US-20120264935-A1 SYNTHESIS OF LIGANDS FOR USE IN ACTINIDE EXTRACTION THE UNIVERSITY OF READING (GB) 2012-10-18 US claimed
CN-122036755-A High-selectivity synthesis method of imidazothiazolone compounds based on epimer dissolution behavior regulation and control 浙江新和成股份有限公司 2026-05-15 CN disclosed
CN-118290464-A Preparation method of 1, 2-bis (trimethylsiloxy) cyclohexene 杭州鑫富科技有限公司 2024-07-05 CN disclosed
CN-118290464-A Preparation method of 1, 2-bis (trimethylsiloxy) cyclohexene 杭州鑫富科技有限公司 2024-07-05 CN disclosed
CN-118290464-A Preparation method of 1, 2-bis (trimethylsiloxy) cyclohexene 杭州鑫富科技有限公司 2024-07-05 CN disclosed
US-20180065990-A1 PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND DSM IP ASSETS B.V. (NL) 2018-03-08 US disclosed
CN-104592284-A 1,2-bis(trimethylsilyloxy)cyclohexene, and preparation method thereof XINYAQIANG SILICON CHEMISTRY JIANGSU CO LTD 2015-05-06 CN disclosed
CN-104592284-A 1,2-bis(trimethylsilyloxy)cyclohexene, and preparation method thereof XINYAQIANG SILICON CHEMISTRY JIANGSU CO LTD 2015-05-06 CN disclosed
EP-1219625-B1 Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- perhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds COUNCIL SCIENT IND RES (IN) 2006-05-17 EP disclosed
US-6486328-B1 Substituted 2-[-6-benzyl-5-oxo-3-phenyl-(3s,7s, 7aR)-perhydroimidazol[1,5-c][1,3]thiazol-7yl] compounds COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-11-26 US disclosed
EP-1219625-A1 Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- pherhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds Council of Scientific and Industrial Research (IN) 2002-07-03 EP disclosed
US-6316634-B2 REACTING 3-ALKOXY/HYDROXY-2-HALO-CYCLOHEPTEN-1-ONE WITH ALKYLAMINIDINE HALIDE TO FORM CYCLOHEPTIMIDAZOLE COMPOUND KOTOBUKI PHARMACEUTICAL CO LTD (JP) 2001-11-13 US disclosed
US-6278027-B1 AS CHEMICAL INTERMEDIATES IN PREPARATION OF DRUGS SUCH AS CYCLOHEPTIMIDAZOLE DERIVATIVES KOTOBUKI PHARMACEUTICAL CO LTD (JP) 2001-08-21 US disclosed
US-20010008944-A1 Method for preparing cycloheptimidazoles TOMIYAMA TSUYOSHI (JP) 2001-07-19 US disclosed
US-4806648-A Efficient synthesis of cyclic cis-vicinal teritiary diamines OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1989-02-21 US disclosed