Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741860 | 0.94 | MAPT (0.52) | ALOX15HSD17B10USP2LMNACYP1A2 | |
| SCHEMBL5742562 | 0.93 | MAPT (0.53) | ALOX15HSD17B10LMNAALDH1A1AGPAT2 | |
| SCHEMBL5741832 | 0.92 | AGPAT2 (0.46) | ALOX15HSD17B10USP2LMNACYP1A2 | |
| SCHEMBL5740342 | 0.92 | AGPAT2 (0.59) | ALOX15HSD17B10AGPAT2TP53MAPT | |
| SCHEMBL5741580 | 0.91 | ACP1 (0.48) | ALOX15HSD17B10USP2LMNACYP1A2 | |
| SCHEMBL5744514 | 0.89 | AGPAT2 (0.47) | LMNAAGPAT2TP53MAPTACP1 | |
| SCHEMBL5740176 | 0.88 | AGPAT2 (0.56) | ALOX15HSD17B10LMNAAGPAT2TP53 | |
| SCHEMBL5743457 | 0.88 | ACP1 (0.54) | ALOX15HSD17B10AGPAT2TP53MAPT | |
| SCHEMBL5741921 | 0.87 | AGPAT2 (0.51) | LMNAAGPAT2TP53MAPTACP1 | |
| SCHEMBL5743121 | 0.86 | AGPAT2 (0.55) | ALOX15HSD17B10AGPAT2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |