Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 15/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741860 | 0.93 | MAPT (0.52) | AGPAT2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL5742562 | 0.92 | MAPT (0.53) | AGPAT2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL5740482 | 0.92 | ALOX15 (0.48) | AGPAT2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL5743121 | 0.91 | AGPAT2 (0.55) | AGPAT2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL5741580 | 0.89 | ACP1 (0.48) | AGPAT2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL5742556 | 0.88 | AGPAT2 (0.61) | AGPAT2HSP90AA1HSP90AB1TP53MAPT | |
| SCHEMBL5743347 | 0.87 | AGPAT2 (0.57) | AGPAT2TP53MAPTHPGDALOX15 | |
| SCHEMBL5742912 | 0.86 | AGPAT2 (0.59) | AGPAT2TP53MAPTACP1 | |
| SCHEMBL5742005 | 0.86 | AGPAT2 (0.59) | AGPAT2TP53MAPTACP1 | |
| SCHEMBL5741832 | 0.86 | AGPAT2 (0.46) | AGPAT2HSP90AA1HSP90AB1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339706-B1 | N-TYPE CALCIUM CHANNEL ANTAGONISTS FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2006-04-19 | — | — | EP | disclosed |