Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.69 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702124 | 0.89 | CNR2 (0.65) | NR1I2ESR1KMT2AMEN1NR3C1 | |
| SCHEMBL5330652 | 0.81 | ESR1 (0.78) | NR1I2ESR1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10438567 | 0.80 | ESR1 (0.79) | NR1I2ESR1KMT2AMEN1L3MBTL1 | |
| SCHEMBL15672854 | 0.80 | NR1I2 (0.48) | NR1I2ESR1KMT2AMEN1CNR2 | |
| SCHEMBL15086440 | 0.79 | TDP1 (0.59) | NR1I2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL5189511 | 0.77 | ESR1 (0.80) | NR1I2ESR1KMT2AL3MBTL1LMNA | |
| SCHEMBL2006245 | 0.77 | ESR1 (0.60) | ESR1KMT2AL3MBTL1TSHRMAPK1 | |
| SCHEMBL7956823 | 0.77 | NR1I2 (0.55) | NR1I2KMT2AMEN1L3MBTL1NR3C1 | |
| SCHEMBL411162 | 0.76 | HDAC3 (0.55) | NR1I2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL3482968 | 0.76 | LMNA (0.60) | NR1I2ESR1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901996-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | MITSUI CHEMICALS INC (JP) | 2006-02-01 | — | — | EP | disclosed |
| US-6222072-B1 | RACTING IMINE WITH HYDRIDE REAGENT IN PRESENCE OF OPTICALLY ACTIVE METAL COMPOUND, WHEREIN HYDRIDE REAGENT IS A METAL HYDRIDE, REAGENT THAT UNDERGOES METAL EXCHANGE, METAL TRIALKOXY HYDRIDE COMPLEX OR METAL(TRICARBOXYLIC ACID)HYDRIDE | MITSUI CHEMICALS INC. (JP) | 2001-04-24 | — | — | US | disclosed |
| EP-0901996-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | Mitsui Chemicals, Inc. (JP) | 1999-03-17 | — | — | EP | disclosed |