SCHEMBL9702124

SCHEMBL9702124

Cc1ccc(S(=O)(=O)N(CCc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.65
NR1I2 O75469 1/20 0.61
CNR1 P21554 2/20 0.58
NR3C1 P04150 1/20 0.58
ALDH1A1 P00352 1/20 0.58
LMNA P02545 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
CA12 O43570 1/20 0.55
CA9 Q16790 1/20 0.55
ESR1 P03372 3/20 0.55
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
KEAP1 Q14145 1/20 0.54
NFE2L2 Q16236 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5740587 0.89 NR1I2 (0.69) CNR2NR1I2NR3C1ALDH1A1LMNA
SCHEMBL8224221 0.84 ESR1 (0.75) CNR2CNR1NR3C1ALDH1A1LMNA
SCHEMBL28029865 0.83 CA12 (0.57) CNR2CNR1NR3C1ALDH1A1LMNA
SCHEMBL8466425 0.82 ESR1 (0.76) CNR2NR1I2CNR1CA12CA9
SCHEMBL14502622 0.82 KEAP1 (0.66) CNR2CNR1LMNACA12CA9
SCHEMBL5604160 0.81 ESR1 (0.73) CNR2NR1I2CNR1ALDH1A1CA12
SCHEMBL9186142 0.81 ESR1 (0.58) CNR2CNR1NR3C1ALDH1A1LMNA
SCHEMBL7568114 0.80 CNR2 (0.48) CNR2NR1I2CNR1CA12CA9
SCHEMBL4335752 0.80 KMT2A (0.62) CNR2CNR1NR3C1ALDH1A1LMNA
SCHEMBL9185927 0.79 ALDH1A1 (0.56) CNR2CNR1NR3C1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106718-A Heat resistant relief structures CIBA-GEIGY CORPORATION (US) 1992-04-21 US disclosed
EP-0364949-A2 Heat-stable positive photoresist CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed