Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RORC | P51449 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | CNR2 | P34972 | 3/20 | 0.61 |
| ▸ | PTGES | O14684 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295367 | 0.88 | ESR1 (0.88) | ESR1NR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3278663 | 0.85 | PTGES (0.84) | ESR1NR3C1MEN1KMT2AALDH1A1 | |
| SCHEMBL3047865 | 0.85 | PTGES (0.84) | ESR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1963814 | 0.84 | MEN1 (0.62) | ESR1NR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6295954 | 0.84 | ESR1 (0.71) | ESR1NR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1964511 | 0.84 | MEN1 (0.62) | ESR1NR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2189346 | 0.82 | LMNA (0.85) | ESR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL10250146 | 0.82 | LMNA (1.00) | ESR1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL5740587 | 0.81 | NR1I2 (0.69) | ESR1NR3C1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6121815 | 0.81 | PGR (0.73) | ESR1NR3C1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110171-A1 | SUBSTITUTED N-BENZYL-N-PHENYLBENZENESULPHONAMIDES FOR TREATING VIRAL INFECTIONS | BAYER HEALTHCARE AG (DE) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007110171-A1 | SUBSTITUTED N-BENZYL-N-PHENYLBENZENESULPHONAMIDES FOR TREATING VIRAL INFECTIONS | BAYER HEALTHCARE AG (DE) | 2007-10-04 | — | — | WO | disclosed |