Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5741119 | 0.81 | MAPT (0.56) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL5740655 | 0.81 | KMT2A (0.56) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL20945460 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL14295968 | 0.77 | MAPT (0.50) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL25179738 | 0.76 | NPSR1 (0.68) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL27936277 | 0.76 | MAPT (0.68) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL3262241 | 0.73 | MAPT (0.68) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL20945432 | 0.73 | MAPT (0.51) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL2287907 | 0.72 | NPSR1 (0.63) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL20945441 | 0.72 | MAPT (0.47) | MAPTMEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | UNIVERSITY OF PUERTO RICO (US) | 2022-09-20 | — | — | US | disclosed |
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | UNIVERSITY OF PUERTO RICO (US) | 2022-09-20 | — | — | US | disclosed |
| US-20200352941-A1 | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTI-CANCER AND ANTI-MIGRATORY AGENTS | UNIV PUERTO RICO (US) | 2020-11-12 | — | — | US | disclosed |
| US-20200352941-A1 | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTI-CANCER AND ANTI-MIGRATORY AGENTS | UNIV PUERTO RICO (US) | 2020-11-12 | — | — | US | disclosed |
| US-10729689-B2 | Carbazole EHop-016 derivatives as anti-cancer and anti-migratory agents | UNIVERSITY OF PUERTO RICO (US) | 2020-08-04 | — | — | US | disclosed |
| US-10729689-B2 | Carbazole EHop-016 derivatives as anti-cancer and anti-migratory agents | UNIVERSITY OF PUERTO RICO (US) | 2020-08-04 | — | — | US | disclosed |
| US-20190125746-A1 | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTI-CANCER AND ANTI-MIGRATORY AGENTS | UNIVERSITY OF PUERTO RICO (PR) | 2019-05-02 | — | — | US | disclosed |
| US-20190125746-A1 | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTI-CANCER AND ANTI-MIGRATORY AGENTS | UNIVERSITY OF PUERTO RICO (PR) | 2019-05-02 | — | — | US | disclosed |
| EP-1380582-B1 | FSH mimetics for the treatment of infertility | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-14 | — | — | EP | disclosed |
| EP-1102763-B1 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | APPLIED RESEARCH SYSTEMS (AN) | 2004-10-13 | — | — | EP | disclosed |
| EP-1380582-A1 | FSH mimetics for the treatment of infertility | Applied Research Systems ARS Holding N.V. (AN) | 2004-01-14 | — | — | EP | disclosed |
| US-6653338-B2 | Heterocyclic carboxamide compounds | APPLIED RESEARCH SYSTEMS ARS HOLDING N.A. (NL) | 2003-11-25 | — | — | US | disclosed |
| US-20020147345-A1 | FSH mimetics for the treatment of infertility | MERCK SERONO SA (CH) | 2002-10-10 | — | — | US | disclosed |
| US-6423723-B1 | ORAL BIOAVAILABILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N. A. (NL) | 2002-07-23 | — | — | US | disclosed |
| EP-1102763-A2 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | Applied Research Systems ARS Holding N.V. (AN) | 2001-05-30 | — | — | EP | disclosed |
| US-6235755-B1 | FOLLICLE STIMULATING HORMONE ANTAGONIST | APPLIED RESEARCH SYSTEMS ARS HOLDING N.A. (AN) | 2001-05-22 | — | — | US | disclosed |
| WO-2000008015-A2 | FSH MIMETICS FOR THE TREATMENT OF INFERTILITY | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352941-A1 | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTI-CANCER AND ANTI-MIGRATORY AGENTS | CDC42, ARHGEF2, ARHGDIB | MAPT 4054/4885MEN1 1935/4885KMT2A 3497/4885 |
| US-11446299-B2 | Carbazole EHop-016 derivatives as anticancer and anti-migratory agents | CDC42, ARHGEF2, HRAS | MAPT 3790/4885MEN1 1521/4885KMT2A 3337/4885 |
| US-20020147345-A1 | FSH mimetics for the treatment of infertility | FSHR, GNRHR, LHCGR | MAPT 4853/4885MEN1 1919/4885KMT2A 297/4885 |
| US-20190125746-A1 | NOVEL CARBAZOLE EHOP-016 DERIVATIVES AS ANTI-CANCER AND ANTI-MIGRATORY AGENTS | CDC42, ARHGEF2, HRAS | MAPT 3896/4885MEN1 2021/4885KMT2A 3051/4885 |
| US-10729689-B2 | Carbazole EHop-016 derivatives as anti-cancer and anti-migratory agents | CDC42, ARHGEF2, GDI2 | MAPT 3908/4885MEN1 1556/4885KMT2A 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.